Nuedexta (Dextromethorphan Hydrobromide)
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Dextromethorphan Hydrobromide Information
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Before taking dextromethorphan and quinidine,
- tell your doctor and pharmacist if you are allergic to dextromethorphan, quinidine (Quinidex), quinine (Qualaquin), mefloquine (Lariam), any other medications, or any of the ingredients in combination dextromethorphan and quinidine capsules. Ask your pharmacist for a list of the ingredients.
- tell your doctor if you are taking mefloquine (Lariam), pimozide (Orap), quinine (Qualaquin) thioridazine, or or another product containing quinidine (Quinidex). Your doctor will probably tell you not to take dextromethorphan and quinidine if you are taking one or more of these medications.
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: antidepressants including clomipramine (Anafranil), desipramine (Doxepin, Sinequan), fluoxetine (Prozac, Sarafem), nefazodone, and paroxetine (Paxil, Pexeva); aprepitant (Emend); clarithromycin (Biaxin, Prevpac); cough and cold medications containing dextromethorphan; cisapride; digoxin (Lanoxin, Digitek); erythromycin (E.E.S. E-Mycin, Erythrocin); fluconazole (Diflucan); itraconazole (Sporanox); ketoconazole (Nizoral); certain medications for human immunodeficiency virus (HIV) such as atazanavir (Reyataz), amprenavir (Agenerase), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, in Kaletra), and saquinavir (Invirase); medications for irregular heart beat such as amiodarone (Cordarone),diltiazem (Cardizem, Cartia, Tiazac, others), disopyramide (Norpace), dofetilide (Tikosyn), procainamide (Procanbid, Pronestyl),sotalol (Betapace), and verapamil (Calan, Covera, Isoptin, Verelan, in Tarka); medications for pain such as codeine, hydrocodone (in Hydrogesic, Lorcet, Lortab, Vicodin, Zydone, others), and methadone; moxifloxacin (Avelox); sparfloxacin (Zagam); and teliththromycin (Ketek). Also tell your doctor or pharmacist if you are taking the following medications or have stopped taking them within the past two weeks: MAO inhibitors including isocarboxazid (Marplan), linezolid (Zyvox), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl), and tranylcypromine (Parnate). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with dextromethorphan and quinidine, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
- tell your doctor if you have or have ever had the following conditions while taking quinidine, quinine, or mefloquine: decrease in the number of blood cells in your bone marrow, lupus (a condition in which the body attacks its own tissues causing damage and swelling), or hepatitis (swelling of the liver). Also tell your doctor if you have or have ever had abnormal heart rhythms or heart failure. Your doctor will probably tell you not to takedextromethorphan and quinidine.
- tell your doctor if you have or have ever had myasthenia gravis (a disorder of the nervous system that causes muscle weakness), a history of street drug use or prescription drug misuse, high blood pressure, a stroke, low levels of potassium or magnesium in your blood, or heart, kidney, or liver disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking the combination of dextromethorphan and quinidine, call your doctor.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking dextromethorphan and quinidine.
- you should know that dextromethorphan and quinidine may make you dizzy. It is important to be careful to avoid falls while taking this medication.
- ask your doctor about the safe use of alcoholic beverages while you are taking dextromethorphan and quinidine. Alcohol can make the side effects from this medication worse.
- stomach pain
- dry eyes or mouth
- muscle spasms
- swelling of the hands, feet, ankles, or lower legs
- frequent, painful, or difficult urination
- cloudy or strong-smelling urine
- unusual bleeding or bruising
- muscle or joint pain
- swelling of the face, throat, tongue, or lips
- swollen lymph nodes
- difficulty breathing
- fast heart beat